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 년도별 목차보기 |
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| 발행년도/권호 |
2018 년 / 권호: V.30,no.2,Jun |
| 논문제목1(원어) |
미더덕껍질의 재생셀룰로오스를 이용한 의료용 섬유의 제조 및
생체적합성 |
| 논문제목2(타언어) |
Preparation and Biocompatibility of Medical Fiber from Novel
Regenerated Cellulose from Styela clava tuni |
| 저자(원어) |
송성화, 김지은, 최준영, 박진주, 이미림, 송보람, 이예찬, 김홍성, 이재호, 임용1, 황대연, 정영진 |
| 저자(타언어) |
Sung Hwa Song, Ji Eun Kim, Jun Young Choi, Jin Ju Park, Mi Rim Lee, Bo Ram Song, Yechan Lee, Hong Sung Kim, Jae Ho Lee, Yong Lim1, Dae Youn Hwang and Young Jin Jung |
| 소속(원어) |
부산대학교 바이오소재과학과, 1동의대학교 임상병리학과 |
| 소속(타언어) |
Pusan National University, Dong-Eui University |
| 시작/끝
페이지 |
117 ~ 129 총페이지 : 13 |
| 언어(원어) |
Korean |
| 초록 |
Abstract Cellulose has been widely applied into various medical fields including scaffolding,
tissue engineering and tissue formation. In this study, we manufactured cellulose
medical fiber from Styela clava tunics(SCT-CS) and analyzed the tensile strength, elongation
at break, fluid uptake and surface morphology. And then, the biocompatibility and
toxicity of SCT-CS were measured in Sprague-Dawley(SD) rats after the implantation for
30, 60 and 90 days. The level of tensile strength and fluid uptake were lower in SCT-CS
than chromic catgut(CCG), while elongation at break level were maintained the higher in
SCT-CS. Also, the roughness with pronounced surface patterns as a result of in vivo
degradation was significantly greater in CCG than this of SCT-CS although these levels
gradually appeared with time in both groups. After implantation for 90 days, SCT-CS and
CCG was successfully implanted around muscle of thigh without any significant immune
response. Furthermore, no significant alterations were measured in serum parameters
and the specific pathological features induced by most toxic compounds for liver and kidney
toxicity. Therefore, these results suggest that SCT-CS showing good biocompatibility
and non-toxicity can be successfully prepared from cellulose powder of SCT as well as
has the potential for use as a powerful biomaterial for medical sutures. |
| 키워드 |
Keywords medical fibers, cellulose, Styela clava tunics, physical properties, biocompatibility |
| 학회지 |
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| Reference |
http://www.koreascience.or.kr/article/ArticleFullRecord.jsp?cn=OSGGBT_2018_v30n2_117&ordernum= |
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